Cellular OS
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04Choline donor

Citicoline

CDP-choline

Choline and cytidine donor for phospholipid synthesis and acetylcholine availability.

Primary module
Brain Performance
Protocol status
Validated · current
Evidence stage
Emerging
Protocol version
Personal Protocol v2.0
Last reviewed
Pending scientific review
04.01Doses

Personal, research and authoritative doses are always shown separately. They must never be combined into a single value.

Jim's personal dose
500 mg (baseline)
Up to 1,000 mg on high cognitive-demand days

Jim's personal protocol dose. Not a general dosage recommendation.

Doses in linked research
Research review pending

Doses used in referenced studies are extracted per source and may differ from personal use.

Authoritative recommendation
Not applicable / review pending

Shown only when a relevant authoritative reference (e.g. NIH ODS) publishes one and it has been verified against this record.

04.02Why it is here

Role in the operating system

Choline and cytidine donor for phospholipid synthesis and acetylcholine availability.

Intended outcome: Support attention and cognitive performance during demanding cognitive work.

Evidence remains bounded by the specific populations, formulations, doses and durations studied. Investigation is ongoing.

04.03Biological mechanism

Proposed mechanism

Research review pending

This section has not yet completed scientific review. No conclusion is currently published.

04.04Expected benefits

Expected benefits

Research review pending

This section has not yet completed scientific review. No conclusion is currently published.

04.05Safety and interactions

Safety, contraindications and interactions

Research review pending

This section has not yet completed scientific review. No conclusion is currently published.

04.06Biomarkers

Relevant biomarkers

Research review pending

This section has not yet completed scientific review. No conclusion is currently published.

04.07Decision history

Decision history

Research review pending

This section has not yet completed scientific review. No conclusion is currently published.

04.08Primary sources

Linked research

Primary studySource verified

Citicoline and Memory Function in Healthy Older Adults

PMID 33978188
Detailed extraction (authors, journal, year, population, dose, duration, results, limitations, funding, conflicts) is pending scientific review. Only the source identifier and title are currently confirmed.
Scientific disclaimer

The Cellular Performance Operating System documents an individual educational and personal performance framework. It is not medical advice, diagnosis or treatment. Personal protocol doses are not general recommendations. Supplement use, laboratory testing and medical decisions should be reviewed with an appropriately qualified healthcare professional.

Evidence may apply only to the specific populations, formulations, doses and durations studied.